WebPirmohamed M, Kitteringham NR, Park BK. Idiosyncratic reactions to antidepressants: a review of the possible mechanisms and predisposing factors. Pharmacol Ther. 1992; 53 (1):105–125. [Google Scholar] Pisciotta AV. Immune and toxic mechanisms in drug-induced agranulocytosis. Semin Hematol. 1973 Oct; 10 (4):279–310. [Google Scholar] Web21 mrt. 2024 · Drug-induced liver injury (DILI) is an adverse toxic drug reaction resulting in liver injury. It is an uncommon occurrence with an estimated incidence of 14–19 cases per 100,000 population, accounting for less than 1% of acute liver injury (ALI). 1 Nevertheless, DILI is the most common cause of acute liver failure (ALF) in the West, with a case …
Cureus Idiosyncratic Drug Reaction: A Rare Mechanism of …
WebHow does idiosyncratic reaction affect medication actions? Idiosyncratic drug reactions appear to not be concentration dependent. A minimal amount of drug will cause an … WebThe reactions are of two types: Photo-toxic :- (T-S) Drug or its metabolite Accumulates in the skin, absorbs light and undergoes a Photochemical reaction followed by Photobiological reaction resulting in Tissue damage (sunburn-like), i.e. erythema, edema, blistering , hyper pigmentation, desquamation. teacher board borders
Idiosyncratic drug reactions: a mechanistic evaluation of risk …
Web5 dec. 2024 · 2. pharmacology An abnormal reaction to a drug, sometimes specified as genetically determined. 1. A physiological or mental peculiarity. 2. A tendency to react … Web2 jun. 2024 · In contrast, some adverse reactions may not vary depending upon the dose of a drug. Idiosyncratic: An idiosyncratic reaction is one that is both undesirable and not … Web32 > REVIEW www.sada.co.za / SADJ Vol. 78 No.1 Adverse drug reactions, a guide for dentists ABSTRACT Adverse drug reactions (ADRs) are unintended or harmful effects due to the use of a medicine. teacher board exam 2022 result