WebDec 30, 2013 · Flavivirus Entry Receptors: An Update 1. Introduction. Within the Flaviviridae family, the genus, Flavivirus, encompasses more than 70 enveloped … WebFlaviviruses include virus species that are major public health threats worldwide. To determine the immunity landscape of these viruses, seroprevalence studies are often performed using IgG ELISA, which is a simple and rapid alternative to the virus neutralization test. In this review, we aim to describe the trends in flavivirus IgG ELISA …
Viral receptors for flaviviruses: Not only gatekeepers
WebFlaviviruses enter host cells by endocytosis initiated when the virus particles interact with cell surface receptors. The current model suggests that flaviviruses use at least two … WebMar 1, 2024 · Several different cell surface factors such as integrins and claudin-1 are also essential receptors for the attachment of the viruses, and other receptors such as mannose and C-type lectin domain family (CLEC5A) are involved in entry of flaviviruses (Perera-Lecoin et al., 2013) (Liu et al., 2009). These host factors. Concluding remarks … proflay
The interactions of flaviviruses with cellular receptors: Implications ...
WebAmongst the entry receptors postulated to be involved in flavivirus entry, the best characterized to date include α v β 3 integrins (17, 18), C-type lectin receptors (CLR) (19–23), phosphatidylserine receptors TIM (T-cell … WebSep 30, 2024 · The binding of the flavivirus to surface entry receptors such as heparan sulfate, ... Meertens, L.; Carnec, X.; Amara, A. Flavivirus entry receptors: An update. Viruses 2013, 6, 69–88. ... After the binding of E glycoproteins to cell-surface entry receptors, the attached virion is internalized into the cell via clathrin-dependent … WebApr 13, 2024 · Flaviviruses bind to receptors and attach to the cell surface, then enter the endosome in a clathrin-dependent manner and finalizes the viral entry process after fusion with the cell membrane in a low pH environment. Small molecules, antibodies or peptides can inhibit flavivirus entry by targeting the above processes. kwsp ipoh opening hours