Cyp6a2
WebMar 23, 2024 · Background: Mechanical allodynia (MA) is one of the leading clinical symptoms of painful diabetic peripheral neuropathy (PDPN), which is a primary reason for non-traumatic amputations, foot ulceration, and gait abnormalities in patients with diabetes. However, the pathogenic mechanisms of MA have not yet been fully elucidated, and … WebSep 25, 2024 · 本发明属于生物技术领域，具体涉及烟粉虱creb转录因子，以及编码基因和重组载体、重组细胞系、重组菌株，以及检测烟粉虱对吡虫啉抗性或敏感性的方法。背景技术烟粉虱bemisiatabaci(gennadius)是世界性的农业害虫，其危害主要包括直接刺吸植物汁液；传播植物病毒；分泌蜜露导致煤污病等。烟粉虱 ...
Cyp6a2
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WebMar 23, 2004 · Three point mutations R335S, L336V and V476L, distinguish the sequence of a cytochrome P450 CYP6A2 variant assumed to be responsible for 1,1,1-trichloro-2,2-bis-(4′-chlorophenyl)ethane (DDT) resistance in the RDDT R strain of Drosophila melanogaster.To determine the impact of each mutation on the function of CYP6A2, the … The psiCHECK-2 dual fluorescent reporter system (Promega, Madison, WI, USA) was used to determine any interaction of miR-310s with putative target binding sites in Cyp6g1 and Cyp6g2. The psiCHECK-2 system incorporates Renilla luciferase as a reporter gene and firefly luciferase as a control to normalize for … See more The DDT-susceptible Canton-S, the low-level DDT-resistant 91-C, and the highly DDT-resistant 91-R strains of Drosophila have been … See more First-strand cDNA synthesis was performed using the miScript II RT kit (Qiagen). Each synthesized cDNA sample was then used as a template for RT-qPCR reactions using the miScript SYBR Green PCR Kit (Qiagen) … See more A set of mirVana mimics were synthesized for miR-310, miR-311, miR-312, and miR-313 by Invitrogen (Ambion, Life Technologies) at a … See more One-day-old female 91-R (90 flies per each injection) were injected separately with miR-310s mimics, NCsiRNA, and DEPC-water using … See more
WebOnly a handful of P450 genes have been functionally characterized from the approximately 90 recently identified in the genome of Drosophila melanogaster. Cyp6a8 encodes a 506 … WebApr 1, 2004 · The CYP6A2vSVL enzyme had an enhanced metabolism of DDT, producing dicofol, dichlorodiphenyldichloroethane and dichlorodiphenyl acetic acid. The apparent affinity of the enzymes CYP6A2wt and CYP6A2vSVL for DDT and testosterone was not significantly different as revealed by the type I difference spectra.
WebJul 25, 2024 · 1. Introduction. Accounting for 85-90% of primary liver malignancy, hepatocellular carcinoma (HCC) is the fifth most common tumor worldwide and the second most common cause of cancer-related death [1–4].Over the last 20 years, the incidence of HCC has been rising in the United States and China [1, 2].Given the complexity of the … WebFeb 28, 2024 · Nanostructures. DN and GN powders were purchased from Skyspring Nanomaterials Inc. (Houston, TX, USA). Both nanoparticles were produced by the explosive method and synthesized to 3–4 nm.
Web钱雨农，叶 鑫，王圣印 (浙江农林大学农业与食品科学学院，浙江杭州 311300) 螺虫乙酯(spirotetramat)是由拜耳公司(Bayer)开发的一类新型内吸性杀虫、杀螨剂[1]，于2011年在大陆地区取得正式登记，与螺螨酯(spirodiclofen)及螺甲螨酯(spiromesifen)同属季酮酸类化合物[2-3]，与之具有相似的化学结构和作用机制[4 ...
WebMar 23, 2009 · The CYP6A2 protein produced in this system metabolized aldrin and heptachlor to their epoxides and metabolized the insecticide diazinon by desulfuration to … iosh group trainingWebBarbital (or barbitone), marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate.It was used as a sleeping aid from 1903 until the mid-1950s.The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt (known as medinal, … on the xbox oneWebApr 14, 2024 · Objective: To investigate the dominant metabolic enzymes of six effective components (astragaloside IV, glycyrrhizic acid, calycosin-glucuronide, formononetin, ononin, calycosin-7-O-β-D- glucoside) of Huangqi Liuyi decoction extract (HQD).Methods: Mouse liver microsomes were prepared. The effects of specific inhibitors of CYP450 … on the x appWebApr 14, 2024 · Objective: To investigate the dominant metabolic enzymes of six effective components (astragaloside IV, glycyrrhizic acid, calycosin-glucuronide, formononetin, … on the wyeWebNov 24, 2024 · Overexpression of functional Cyp6a2 was consistently associated with DDT resistance. Luciferase reporter gene assays revealed that an intact Nrf2/Maf binding site … iosh governance structureWebJul 1, 2014 · Molecular analysis identified five Cyp6a2 alleles (Cyp6a2 (Canton) (-S-1) , Cyp6a2 (Canton) (-S-2) , Cyp6a2 (91-C) , Cyp6a2 (91-R) and Cyp6a2 (Wisconsin) (-) (WD) ) from four D.... iosh guidance on communication 2015WebDive into the research topics of 'Nrf2/Maf-binding-site-containing functional Cyp6a2 allele is associated with DDT resistance in Drosophila melanogaster'. Together they form a unique fingerprint. Sort by Weight Alphabetically Agriculture & Biology DDT (pesticide)100% iosh future leaders conference