Cisplatin hyponatriämie

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August undefined, 2024

WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum … WebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated with a sodium supplement. We also summarize the key diagnostic features and the most common differential diagnoses for hyponatremia syndrome.

[Hyponatremia during treatment with cisplatin] - PubMed

WebJul 7, 2024 · 1 Department of Pharmacy, Showa University Hospital, Tokyo, Japan. 2 Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan. 3 Department of Surgery, Division of General and Gastroenterological Surgery, School of Medicine, Showa University, Tokyo, Japan. 4 Showa University Esophageal … WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose … chinese restaurant phenix city al

Cisplatin - StatPearls - NCBI Bookshelf

WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … WebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt wasting syndrome (RSWS) [1]. It is unclear why it occurs but it is believed that pharmacogenetics plays an essential role. WebNational Center for Biotechnology Information chinese restaurant perth amboy nj

Diagnosis and Management of Hyponatremia in Cancer Patients

Renal salt-wasting syndrome in a patient with cisplatin-induced ...

WebSep 18, 2024 · NCBI Bookshelf Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less. grand summit resort hotel - attitashWebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt … chinese restaurant pine bush ny

"WebJun 11, 2024 · INTRODUCTION Hyponatremia represents a relative excess of water in relation to sodium. It can be induced by a marked increase in water intake (primary polydipsia) and/or by impaired water excretion due, for example, to advanced kidney failure or persistent release of antidiuretic hormone (ADH). (See "Causes of hypotonic … " - Cisplatin hyponatriämie

Cisplatin hyponatriämie

WebNov 1, 1997 · Cisplatin is one of the most widely used agents in cancer treatment. Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of … WebKeywords: Cisplatin, Dehydration, Hyponatremia, Renal salt wasting, Siadh. Case Presentation: A 63-year-old male presents to the hospital with complaints of one-day history of weakness, dizziness. His outpatient blood work demonstrated a serum sodium level of 124 mEq/L, and a creatinine of 3.1 mg/dL. His medical history was significant for high ...

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WebCisplatin-induced hyponatremia and renal sodium wast-ing. Acta Oncol 1995;34:264-5. 12. Cao L, Joshi P, Sumoza D. Renal salt-wasting syndrome in a patient with cisplatin-induced hyponatremia. Am J WebNational Center for Biotechnology Information

WebHyponatremia is one of the common electrolyte disorders associated with cisplatin (CDDP) administration. We report here two cases of hyponatremia associated with CDDP. Case 1 : A 75-year-old man with urothelial carcinoma of bladder (cT3N1M0) underwent neoadjuvant chemotherapy with CDDP and gemcitabi … WebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium reabsorption, which in rare cases may lead to hyponatremia via salt wasting nephropathy [ 41 ].

WebFeb 1, 1999 · Hypomagnesemia is a well known side-effect in patients receiving cisplatin-containing chemotherapy. Cisplatin induces hypomagnesemia through its renal toxicity possibly by a direct injury to mechanisms of magnesium reabsorption in the ascending limb of the loop of Henle as well as the distal tubule. WebHyponatremia was defined and graded using the Common Terminology Criteria for Adverse Events, version 4.0, as follows: a serum sodium concentration from lower limit of normal to 130 mEq/L, grade 1; …

WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignancies. 1,2 Approximately 20% of all cancer patients are prescribed platinum-based chemotherapeutics. 3 Although considered highly effective, cisplatin is also a dose-dependent nephrotoxin, …

WebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, hypophosphatemia, Electrolyte disorders with platinum … chinese restaurant peterborough ontarioWebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, … grand summit resort hotel attitashWebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. … grand summit resort hotelWebApr 27, 2024 · Hyponatremia is a common adverse effect induced by cisplatin. Caution should be exercised with patients with a low sodium level before starting chemotherapy. Hyponatremia can be associated with other chemotherapy-related adverse effects, and it should therefore be treated correctly. Introduction chinese restaurant plymouth barbicanWebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … grand summit resort hotel maineWebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt … grand summit resort hotel newry meWebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium … grand summit sunday river maine