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Burnettramic acid

WebDec 12, 2024 · The recently discovered antibiotic burnettramic acid A (1) and three new congeners, burnettramic acids C-E (2-4), were identified from the co-cultures of two … WebBurnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated from A. burnettii that has anticancer activity. It is cytotoxic to NS …

Burnettramic Acid A (CAS 2334483-46-2)

WebJan 28, 2024 · A chemical work-up of the SPE-fractions of its dichloromethane subextract led to the isolation of a new PKS-NRPS hybrid macrolactone, versicolide A ( 1 ), a new quinazoline (-)-isoversicomide A ( 3 ), as well as three known compounds, burnettramic acid A ( 2 ), cyclopenol ( 4) and cyclopenin ( 5 ). WebBurnettramic acid A is active against the Gram positive bacteria, B. subtilis and S. aureus, with IC50 2.3 and 5.9 µg/mL, respectively. Burnettramic acid A is a potent antifungal … riding with the angels https://theresalesolution.com

Discovery and Heterologous Biosynthesis of the Burnettramic Aci…

WebNov 24, 2024 · Europe PMC is an archive of life sciences journal literature. WebThe burnettramic acids are a new class of antibiotics from an Australian fungus Aspergillus burnettii. The rare bolaamphiphilic scaffold consists of β-d-mannose linked to a pyrrolizidinedione... Webburnettramic acid A biosynthetic gene cluster from Aspergillus sp. CLMG-2024a. Discovery and Heterologous Biosynthesis of the Burnettramic Acids: Rare PKS-NRPS … riding with the braves

Burnettramic Acid A TargetMol

Category:Cyclopiazonic acid - TOKU-E

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Burnettramic acid

(PDF) Mining and characterization of the PKS-NRPS hybrid for ...

WebThe VRPKS-I-6 core gene clustered with burnettramic acid biosynthesis PKS from Aspergillus burnettii and other Aspergillus PKS genes, including A. avenaceus hypothetical protein (KAE8150730) and A ... WebApr 15, 2013 · The structure of burnettramic acid A was revised on the basis of reinterpretation of the nuclear magnetic resonance (NMR) data and chemical …

Burnettramic acid

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WebThe recently discovered antibiotic burnettramic acid A (1) and three new congeners, burnettramic acids C-E (2-4), were identified from the co-cultures of two marine Aspergillus strains. WebDec 12, 2024 · Finally, synthetic pyrimidine antimetabolites such as flucytosine interfere with nucleic acid biosynthesis, but resistance via point mutations in the fungal uracil phosphoribosyltransferase or cytosine deaminase enzymes restricts their application to combination therapy [8]. Open in a separate window Figure 1

WebQuantity. Price. $25.50 - $76.50. Detailed Description. 2,4-Dichlorophenoxyacetic acid (syn: 2,4-D) is plant growth regulator and synthetic auxin. It is a synthetic analog of the naturally occurring auxin indole-3-acetic acid (IAA). As an agricultural phenoxy herbicide, it has been commercially available since 1945 and is an active ingredient ... WebBurnettramic acid A C41H71NO12 CID 146683156 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...

WebBurnettramic acid A is a potent antifungal agent (IC50 0.5 µg/mL and 0.2 µg/mL against C. albicans and S. cerevisiae, respectively). Burnettramic acid A is also active against … WebAug 11, 2024 · Burnettramic acid A (final classification: Ib-A) has a saturated polyketide chain possessing three hydroxyl groups, whereas fusaridione (Ib-D) has a polyene side chain. Among them, burnettramic...

WebByssochlamic Acid is closely related to the mycotoxins rubratoxin B, produced by Penicillium rubrum, and glaucanic acid, isolated from P. glaucum. The reported pharmacology of Byssochlamic Acid is limited to antitumor and phytotoxic activity. Related Products Novobiocic Acid USA Local Phone 360-734-1789 Fax 360-734-0798 …

WebBurnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS … riding with roudy tellurideWebBurnettramic acid A is a fungal metabolite found in A. burnettii which has diverse biological activities. It is active against B. subtilis, S. aureus, C. albicans, and S. cerevisiae (IC50s = 2.3, 5.9, 0.5, and 0.2 µg/ml, respectively). Burnettramic acid A is also cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts ... riding with scratched snowboardriding with the ghost bookWebJan 11, 2024 · Burnettramic acid A aglycone. CAS No. : 2396676-46-1. Biological Activity:Burnettramic acid A aglycone is a fungal metabolite found in Aspergillus burnettii. Research Area:Others. Targets:Endogenous Metabolite riding with pvt malone on youtubeWebJun 1, 2024 · Burnettramic acid A (Figure 4) was shown to exhibit comparable activity to amphotericin B against Candida albicans, and characterization of the corresponding biosynthetic cluster has aided in identifying additional fungal strains with the capability of biosynthesizing burnettramic acid analogues. riding with the gang modWebFeb 8, 2024 · Burnettramic acid A (2) was the main constituent of the highly active SPE Fr.8. Its structure was unambiguously confirmed by comparison of its HRMS, NMR and … riding with the devil bookWebBurnettramic acid A is active against the Gram positive bacteria, B. subtilis and S. aureus, with IC50 2.3 and 5.9 µg/mL, respectively. Burnettramic acid A is a potent antifungal agent (IC50 0.5 µg/mL and 0.2 µg/mL against C. albicans and S. cerevisiae, respectively). Burnettramic acid A is also active against murine myeloma NS-1 cell line ... riding with the bulls