WebOpioids can cause sleep-related breathing disorders including central sleep apnea (CSA) and sleep-related hypoxemia; opioid use increases risk of CSA in a dose-dependent … WebThe most frequent primary reasons for switching to alfentanil was uncontrolled pain in 52 (46%) patients and renal impairment in 24 (21%) patients. The median 24-h initial dose of alfentanil was 4 mg (1–20), and the median final 24 …
Pain Management in Renal Failure - Choice of opioid
WebOct 19, 2024 · Present data suggest that clearance of alfentanil is unaltered in renal failure. However, there is an increased free fraction and hence dosage requirements may be less than in the patient with normal renal function. ... The concomitant use of alfentanil and propofol may require a lower dose of Alfentanil 5 mg/ml solution for injection ... WebDose: 0.5-1.5 mcg/kg/min IV; Max: 4 mcg/kg/min; Info: use LBW in obese pts; LBW = lean body wt in kg; refer to Lean Body Weight (Female) and Lean Body Weight (Male) … cranky and flynn save the day playset
Alfenta (Alfentanil for Injection): Uses, Dosage, Side …
Doses should be individualized and titrated to the desired effect according to body weight, physical status, underlying pathological condition, use of other drugs, and type and duration of surgical procedure, and anesthesia: 12 years or older: 1. SPONTANEOUSLY Breathing/Assisted Ventilation: 1. … See more Doses should be individualized and titrated to the desired effect according to body weight, physical status, underlying pathological condition, use of other drugs, and type and duration of surgical procedure, and … See more Use with caution, dosage adjustments may be required; however, no specific guidelines have been suggested. 1. More frequent monitoring for signs of respiratory depression, sedation, and hypotension are recommended due to … See more Initial dose: Reduce usual adult dose by up to 40% to account for reduced clearance and increased sensitivity 1. Subsequent doses … See more Use with caution, dosage adjustments may be required; however, no specific guidelines have been suggested. 1. More frequent monitoring … See more WebOct 25, 2012 · Davis JP, Stiller RL, Cook DR, et al. Effects of cholestatic hepatic disease and chronic renal failure on alfentanil pharmacokinetics in children. Anesth Analg 1989; 68: 579–83. ... Decreased fentanyl and alfentanil dose requirements with age: a simultaneous pharmacokinetic and pharmacodynamic evaluation. J Pharmacol Exp Ther 1987; 240: … WebAlfentanil, fentanyl and sufentanil are synthetic opioid analgesics acting at specific opioid receptors. These opioids are widely used as analgesics to supplement general anaesthesia for various surgical procedures or as primary anaesthetic agents in very high doses during cardiac surgery. ... but not significantly by renal insufficiency or ... diy slow waterer for plants