Albinterferon alfa-2b
Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and produced recombinantly in E. coli in the laboratory of Charles Weissmann at the University of Zurich, in 1980. It was developed at Biogen, and ultimately marketed by Schering-Plough under the trade name Intron-A. It was also produced in 1986 in recombinant human form, in the Center for Genetic Engineering and Biotechnology of … WebAug 25, 2009 · Drug: albinterferon alfa-2b: Experimental: Group 2 ABF656 900ug Q4w Drug: albinterferon alfa-2b: Experimental: Group 3 AB656 1200ug Q4w Drug: albinterferon alfa-2b: Experimental: Group 4 ABF656 1500ug Q4w Drug: albinterferon alfa-2b: Active Comparator: Group 5 Pegasys® 180µg qw Drug: Pegasys®
Albinterferon alfa-2b
Did you know?
WebAlbinterferon (alb-IFN, trade name Albuferon) is a recombinant fusion protein drug consisting of interferon alpha (IFN-α) linked to human albumin. Conjugation to human … WebMar 11, 2009 · Results: Albinterferon alfa-2b has been developed for the treatment of CHC. This agent exhibits a prolonged half-life and duration of antiviral activity that …
WebWe evaluated the efficacy/safety of albinterferon alfa-2b (albIFN), a novel, long-acting, genetic fusion polypeptide of albumin and IFNα-2b. Methods In the phase 3 ACHIEVE-1 … WebAlbinterferon-α-2b (Joulferon) is a recombinant protein consisting of interferon-α-2b fused to human albumin that can be administered every 2 weeks, owing to a longer half-life …
WebOct 1, 2010 · Albinterferon alfa-2b (alb-IFN) is a novel recombinant protein consisting of IFNα-2b that is genetically fused to human albumin. Methods: To test alb-IFN antiviral efficacy, we compared the ... WebInterferon alfa-2b is indicated for the treatment of chronic hepatitis B in patients 1 year of age or older with compensated liver disease. Patients who have been serum HBsAg …
WebJan 1, 2007 · In this randomised trial, peginterferon alfa-2b plus ribavirin was compared with interferon alfa-2b plus ribavirin. 1530 patients with chronic hepatitis C were assigned interferon alfa-2b (3 MU ...
WebThis Phase 2b trial is a randomized, open-label, multi-center, active-controlled, dose-ranging study to evaluate the safety and efficacy of albinterferon alfa-2b administered every four weeks plus daily ribavirin in treatment-naïve patients with genotypes 2 and 3 chronic hepatitis C. 391 patients were randomized in a 4:4:4:3 ratio into four … m\u0026m computers hermanusWebNov 22, 2010 · Albinterferon alfa-2b (albIFN) is a novel genetic fusion protein composed of the mature form of recombinant human albumin (rHA) and the mature form of … how to make stone cutter valheimWebAlbinterferon is a genetic fusion polypeptide of albumin and interferon alfa-2b with a longer half life than pegylated interferons. The phase 2 study comparing different doses of albinterferon alfa-2b and ribavirin with peginterferon alfa-2a and ribavirin indicated similar sustained virologic response rates with a better tolerability of ... m \u0026 m computers greenback lnWebIn a clinical trial led by NIH, researchers found that interferon alfa-2b, a type of immunotherapy, substantially increased the survival of people… Liked by Souradipto … m\u0026m constructors becker mn pppWebALBINTERFERON ALFA-2B UNII: 4DVS4AG4DF Preferred Substance Name: ALBINTERFERON ALFA-2B Synonyms and Mappings 472960-22-8 1-585-SERUM ALBUMIN (HUMAN) FUSION PROTEIN WITH INTERFERON .ALPHA.-2B... m\u0026m computers citrus heightsWebOct 24, 2024 · Ropeginterferon alfa-2b is a novel mono-pegylated interferon that has only one major form as opposed to 8–14 isomers of other on-market pegylated interferon, allowing injection every two or more weeks with higher tolerability. how to make stone countertopsWebAlbinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C Treatment regimens based on the use of interferon-alpha (IFN-alpha) remain the … m\u0026m company website